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A new discovery highlighted a novel part for intracellular MIF in regulating the accumulation of misfolded Cu/Zn superoxide dismutase (SOD1). Mutations in SOD1 are associated with twenty% of the scenarios of familial amyotrophic lateral sclerosis, which can be characterised by lack of motor neurons [seventy two]. Despite the fact that MIF was foun
MIF resources plus the accompanying match pounds may be used only for expenditures developing once the date of final execution on the Grant agreement (successful day). Absorbance was measured at 590 nm. The absorbance correlates linearly to the number of dwelling cells in culture, plus the IC50 value was calculated. Additionally, cell viability